In my day-to-day life, EDS or cataplexy in narcolepsy
How much does EDS or cataplexy in
narcolepsy impact your day-to-day life?
What is your top goal for managing your EDS or
cataplexy in narcolepsy?
How often do you feel you reach this goal?

When it comes to my treatment plan, I am
How satisfied are you with your current
treatment plan?
How ready are you to consider a change to
your treatment?

My Questions About WAKIX^® (pitolisant)
How does WAKIX work? Is WAKIX a stimulant? Is WAKIX a controlled substance?	How is WAKIX taken? How long might it take for WAKIX to work? What are the possible side effects of WAKIX? Do you think WAKIX might be a treatment option for me?

Indications and Usage

WAKIX is a prescription medicine used to treat:

excessive daytime sleepiness (EDS) or cataplexy in adults with narcolepsy.
excessive daytime sleepiness (EDS) in children 6 years of age and older with narcolepsy.

Important Safety Information

Do not take WAKIX if you are allergic to pitolisant or any
ingredient in WAKIX, or if you have severe liver disease.

Please see Important Safety Information
continued on following page and
accompanying Full Prescribing Information.

Important Safety Information (continued)

WAKIX^® (pitolisant) can cause a change in the electrical activity of the heart known as QT prolongation. This is a heart rhythm problem that can lead to an abnormal heartbeat. You have a higher chance of getting QT prolongation if you have certain heart or other medical conditions, or if you take WAKIX with certain medicines. Tell your healthcare provider right away if you have a change in your heartbeat or if you feel dizzy or faint while taking WAKIX.

Tell your healthcare provider about all your medical conditions, including if you have any heart, liver, or kidney problems, or problems with blood levels of your electrolytes, such as potassium or magnesium.

Tell your healthcare provider about all the medicines you take or plan to take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking WAKIX with certain medicines may cause side effects or affect the way each other works.

Hormonal birth control methods may not work while taking WAKIX. Use an alternative non-hormonal birth control method during treatment with WAKIX and for at least 21 days after stopping WAKIX.

Tell your healthcare provider if you are pregnant or planning to become pregnant. You are encouraged to enroll in the WAKIX pregnancy registry if you become pregnant while taking WAKIX. The registry collects information about the health of you and your baby. To enroll or obtain information from the registry, call 1-800-833-7460.

The most common side effects of WAKIX in adults include insomnia, nausea, and anxiety.

The most common side effects of WAKIX in children include headache and insomnia.

These are not all the possible side effects of WAKIX. Call your healthcare provider for medical advice about side effects.

It is not known if WAKIX is safe and effective to treat excessive daytime sleepiness in children under 6 years of age with narcolepsy or to treat cataplexy in people under 18 years of age with narcolepsy.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You can also report negative side effects to Harmony Biosciences at 1-800-833-7460.

Please see accompanying Full Prescribing Information.