Discussion Guides 
and Tools

Start the conversation

Find tools to help you measure the signs and symptoms of excessive daytime sleepiness (EDS) or cataplexy in narcolepsy, as well as guides for talking with your doctor.

Design your discussion

Use this guide to reflect on your needs when it comes to managing your excessive daytime sleepiness (EDS) or cataplexy in narcolepsy to discuss with your healthcare provider.

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Prepare for a virtual

This guide will help you navigate virtual appointments—from setting up your technology to planning what you want to discuss.

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Personalize your

Answer a few quick questions to get a personalized conversation plan about your treatment needs to share at your next appointment.

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Measuring your EDS

If EDS is still interfering with your life, you can use the Epworth Sleepiness Scale (ESS) to assess your level of daytime sleepiness. You can then share the results with your healthcare provider during your next discussion.

Download the scale

Understanding your cataplexy

If you have cataplexy or think you might have cataplexy, you can use these helpful questions to understand how cataplexy may be interfering with your life. You can then share the results with your healthcare provider during your next discussion.


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Indications and usage & Important Safety Information

Important Safety Information

Do not take WAKIX if you are allergic to pitolisant or any ingredient in WAKIX, or if you have severe liver disease.

Tell your healthcare provider about all your medical conditions, including if you have heart rhythm irregularities, were born with a heart condition, or the levels of electrolytes in your blood are too high or too low. WAKIX has an effect on the electrical activity of the heart known as QT/QTc prolongation. Medicines with this effect can lead to disturbances in heart rhythm, which are more likely in patients with risk factors such as certain heart conditions, or when taken in combination with other medicines that affect QT. Tell your healthcare provider about all the other medicines you take.

The risk of QT prolongation may be greater in patients with liver or kidney disease. WAKIX is not recommended in patients with end-stage kidney disease.

The most common side effects seen with WAKIX were insomnia, nausea, and anxiety. Other side effects included headache, upper respiratory infection, musculoskeletal pain, heart rate increased, and decreased appetite. These are not all the possible side effects of WAKIX. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Tell your healthcare provider about all the medicines you take or plan to take, including prescription and over-the-counter medicines. Some medicines can increase the amount of WAKIX that gets into your blood and some medicines can decrease the amount of WAKIX that gets into your blood. The dosage of WAKIX may need to be adjusted if you are taking these medicines.

WAKIX can also decrease the effectiveness of some medicines, including hormonal birth control methods. You should use an alternative non-hormonal birth control method during treatment with WAKIX and for at least 21 days after discontinuation of treatment.

Tell your healthcare provider if you are pregnant or planning to become pregnant. There is a pregnancy exposure registry that monitors pregnancy outcomes in women who are exposed to WAKIX during pregnancy. You are encouraged to enroll in the WAKIX pregnancy registry if you become pregnant while taking WAKIX. To enroll or obtain information from the registry, call 1-800-833-7460.

The safety and effectiveness of WAKIX have not been established in patients less than 18 years of age.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You can also report negative side effects to Harmony Biosciences at 1-800-833-7460.

Please see Full Prescribing Information.

Indications and Usage

WAKIX is a prescription medicine used to treat excessive daytime sleepiness (EDS) or sudden onset of weak or paralyzed muscles (cataplexy) in adults with narcolepsy.


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